Clinical comparison · Cognitive / neuro
Cerebrolysin vs Semax
Cerebrolysin is a neurotrophic peptide mixture with decades of international stroke/TBI use. Semax is an intranasal BDNF-upregulating focus peptide.
Attribute
Cerebrolysin
Semax
Mechanism
Porcine-derived neuropeptide mixture; neurotrophic and neuroprotective across multiple pathways.
ACTH(4-10) analog; upregulates BDNF and NGF for neuroprotection and focus.
Standard dosing
5–30 mL IM/IV daily for 10–20 day cycles.
250–600 mcg intranasal 1–2x daily.
Indications
- Stroke recovery
- TBI
- Cognitive decline
- Cognitive performance
- Focus
- Neuroprotection post-injury
Strengths
- Broad neurotrophic support
- Substantial international clinical data
- Stimulant-like focus without sympathomimetic load
- BDNF upregulation
Cautions
- IM/IV administration only
- Cycled protocol
- Short duration
- Limited long-term data
Choose Cerebrolysin when
Post-stroke, TBI, or measurable cognitive decline warranting an IM/IV cycle.
Wholesale Cerebrolysin →Choose Semax when
Daily focus, work performance, or lighter neuroprotective maintenance.
Wholesale Semax →FAQs
- Can they be sequenced?
- Yes. A Cerebrolysin cycle for acute recovery followed by Semax maintenance is a common neuro-clinic pattern.
- Which has FDA approval?
- Neither in the US. Cerebrolysin is approved in many other countries; Semax is a Russian pharmaceutical.