Clinical comparison · Growth hormone
Ipamorelin vs CJC-1295
This isn't really vs — it's the canonical GHRP + GHRH stack. Comparing side by side helps clarify which one is doing what work in a combined protocol.
Attribute
Ipamorelin
CJC-1295
Mechanism
Selective ghrelin receptor agonist. Clean pulsatile GH release without cortisol/prolactin spike.
GHRH analog; DAC variant binds albumin for ~8-day half-life.
Standard dosing
200–300 mcg SC 1–3x daily, often paired with CJC-1295.
100 mcg with ipamorelin 1–3x daily (no DAC), or 1–2 mg weekly (with DAC).
Indications
- Longevity
- Body composition
- Sleep and recovery
- Longevity
- Body composition
- Recovery adjunct
Strengths
- Selective, clean side-effect profile
- Pairs with any GHRH
- Longer half-life than sermorelin (with DAC)
- Synergy with ipamorelin
Cautions
- Requires multiple daily doses without CJC pairing
- Blunted pulsatility with DAC variant
- Monitor fasting glucose
FAQs
- Is CJC/Ipa one product or two?
- Two compounds, sometimes combined in a single blended vial by the compounding pharmacy for convenience.
- What's a standard combined dose?
- 100 mcg CJC-1295 (no DAC) + 100 mcg ipamorelin SC, 1–3x daily on an empty stomach.