Clinical comparison · IV / longevity
NAD+ vs Glutathione
NAD+ replenishes the coenzyme central to mitochondrial energy production. Glutathione is the master intracellular antioxidant. Different mechanisms, both anchors of modern IV menus.
Attribute
NAD+
Glutathione
Mechanism
Coenzyme central to mitochondrial redox reactions and sirtuin activation. Delivered IV or SC to bypass oral bioavailability limits.
Master intracellular antioxidant; supports phase II detoxification and redox balance.
Standard dosing
100–500 mg IV over 1–3 hours, or 100 mg SC daily.
600–2000 mg IV push, or 200 mg SC/IM 1–3x weekly.
Indications
- Longevity
- Fatigue and recovery
- Neurocognitive support
- Detox support
- Skin brightening
- Oxidative stress
Strengths
- Direct substrate replenishment
- Immediate patient-felt effects with IV
- Broad adjunct across IV menus
- Well-tolerated
Cautions
- Higher cost per session
- IV chair time required
- Sulfur sensitivity
- Effects are supportive, not disease-modifying
Choose Glutathione when
Oxidative stress, detox support, or aesthetic (skin-brightening) protocols.
Wholesale Glutathione →FAQs
- Can NAD+ and glutathione run in the same session?
- Yes. Standard practice is NAD+ drip with glutathione push at the end of the session.
- Which drives revenue better?
- NAD+ carries a higher ticket and stronger patient-felt effect; glutathione is a high-margin add-on.