Clinical comparison · Cognitive / neuro
Selank vs Semax
Both are Russian-origin intranasal neuropeptides. Selank is the anxiolytic; Semax is the focus/BDNF driver.
Attribute
Selank
Semax
Mechanism
Synthetic analog of tuftsin; anxiolytic via GABAergic and neurotrophic pathways.
ACTH(4-10) analog; upregulates BDNF and NGF for neuroprotection and focus.
Standard dosing
250–500 mcg intranasal 2–3x daily.
250–600 mcg intranasal 1–2x daily.
Indications
- Anxiety
- Cognitive support
- Stress resilience
- Cognitive performance
- Focus
- Neuroprotection post-injury
Strengths
- Non-sedating anxiolysis
- Intranasal convenience
- Stimulant-like focus without sympathomimetic load
- BDNF upregulation
Cautions
- Short duration of effect
- Limited long-term data
- Short duration
- Limited long-term data
Choose Semax when
Focus, cognitive performance, or neuroprotective post-concussion protocol.
Wholesale Semax →FAQs
- Can Selank and Semax be used together?
- Yes. Semax in the morning for focus, Selank later in the day for anxiolysis is a common pairing.
- Do they interact with SSRIs?
- No known pharmacokinetic interaction, but coordinate with the prescribing psychiatrist before layering.